I must ask, why the name “Gridless”? Surely HTML/CSS frameworks and grid systems are completely different things? The name almost seems to suggest that the use of a grid is a bad thing. Just the way I perceived it :)
You're right, Gridless is not really the best name for this boilerplate, but I'm not good in choosing names :(
The problem with grid systems is that they include classnames and ids which should be unique to each project. You can still use grids, but please don't use span-x classes, customize the classnames and ids to suit to your project. And doing that isn't impossible or extremely hard, there are a lot of tools out there for that: Sass/Compass, LESS, Blueprint's compress.rb script etc.