The only reason I say that mindset is problematic is because the way you frame your statement is "this can't be done" when what is actually the case is that we have never really tried because there are many other easier problems to solve. I don't think anyone who has spent even a limited amount of time modelling expects to be able to stick a few equations together and have it all work. It is still an open question as to whether we can capture say 95% of the variance in a system using a collection of simplified models or whether we have to go full monte carlo and study models that have the full complexity of the system they represent because you really do need every last single part and can't simplify anything.

There will be novel results no matter what happens, maybe not about c elegans, but certainly about the models themselves.